Christelle Charbel

I am an Assistant Professor and Coordinator of Biology at Polytech-Université La Sagesse. I hold a PhD in Physiology and Physiopathology from the Sorbonne University (Pierre et Marie Curie, UPMC, Paris-France), a Master’s degree in Functional Genomics and Proteomics and a BSc in Biology and Biochemistry from Saint Joseph University (USJ). My research focused on the ontogeny and characteristics of initiating cells in benign skin cancers with particular interest in understanding their developmental origin, molecular profile, and potential for transformation. In parallel with my academic and research activities, I have served as a member of the Technical Committee at the Lebanese Standards Institution (LIBNOR), where I contributed to the formulation and revision of national standards for detergents and cosmetic products, ensuring alignment with international regulations and safety protocols.

Qualifications

• PhD in Physiology and Physiopathology (2013), University of Pierre et Marie Curie (UPMC) – Paris -France
• MSc in Functional Genomics and Proteomics (2009), Saint Joseph University (USJ)
• BSc in Biology and Biochemistry (2007), Saint Joseph University (USJ)
• Training certificate for trainers on “THE FLIPPED CLASSROOM” offered by Agence Universitaire de la Francophonie (AUF-Lebanon)

Professional Experience

Member of technical committee/Microbiological Consultant

Lebanese Standards Institution (LIBNOR) affiliated with the Ministry of Industry-Sin El Fil, Lebanon

September 2017-September 2020

• Contributed in preparing the Lebanese standards for detergents and cosmetics.
• Established dimensions, conventions, symbols, and defined product quality.
• Developed methods for testing and analysis.

Teaching interests

• Cellular and Molecular Biology
• Microbiology and Immunology
• Genetic Engineering
• Biotechnology in Agrifood sector
• Biochemistry

Research interests

• Valorization of Agrifood waste
• Ontogeny and molecular characterization of initiating cells in skin cancer

Publications

• Guégan, S., Kadlub, N., Picard, A., Charbel, C., Coulomb-L’Hermine, A., Rouillé, T., Aractingi, S., Fontaine, R. (2016). Varying proliferative and clonogenic potential in NRAS-mutated congenital melanocytic nevi according to size. Experimental Dermatology, 25: 789–796. https://doi.org/10.1111/exd.13073
• Charbel, C., Fontaine, R., Kadlub, N., Picard, A., Aractingi, S., Guégan, S. (2015). Clonogenic Cell Subpopulations Maintain Congenital Melanocytic Nevi. Journal of Investigative Dermatology, 135, 824–833. https://doi.org/10.1038/jid.2014.437
• Charbel, C., Fontaine, R., Malouf, G., Picard, A., Kadlub, N., El-Murr, N., How-Kit, A., Su, X., Coulomb-L’hermine, A., Tost, J., Mourah, S., Aractingi, S. and Guégan, S. (2014). NRAS mutation is the sole recurrent somatic mutation in large congenital melanocytic nevi. Journal of Investigative Dermatology, 134, 1067–1074. https://doi.org/10.1038/jid.2013.429

• Charbel, C., Fontaine, R., Malouf, G., Picard, A., Kadlub, N., How-Kit, A., Coulomb-L’hermine, A., Tost, J.,  Mourah, S., Aractingi, S. and Guégan, S.(2013): La mutation NRAS est la seule mutation récurrente au sein des naevus congénitaux », Annales de Dermatologie et de Vénéréologie 140(12):S639-S640.

https://doi.org/10.1016/j.annder.2013.09.599

• Fontaine, R., Charbel, C., Kadlub, N., Coulomb, A., Picard, A., Aractingi, S., Guégan, S. (2013) :  Caractérisation des cellules souches initiatrices au sein des naevus congénitaux , Annales de Dermatologie et de Vénéréologie.

https://doi.org/10.1016/j.annder.2013.09.576

Community Services

• Expert in program and laboratory preparation for the lunch of the Faculty of Engineering, Sagesse University (2017-2018).